Creative Brief: CMLase and Age-Related Protein Damage

Work requirements

Details

## Project Create a single-page vertical infographic explaining how researchers engineered an enzyme, CMLase, to remove one specific form of age-related chemical damage from proteins. The piece should feel like a page from a beautifully illustrated scientific field notebook: warm textured paper, restrained color, precise hand-drawn line art, and clear editorial typography. ## Objective Help a general audience understand, at a glance: 1. Some long-lived proteins accumulate chemical damage called advanced glycation end products (AGEs). 2. Researchers engineered CMLase to remove one AGE called CML and restore the affected lysine residue. 3. The enzyme reduced CML in laboratory-treated human tissue samples. 4. This is an early ex-vivo proof of concept, not an anti-aging treatment tested in people. ## Audience Science-curious adults with no specialist background in biochemistry, aging research, or enzyme engineering. Assume readers may know the word “protein” but will not know AGE, CML, lysine, glycation, or directed evolution. ## Key takeaway **Scientists engineered an enzyme that can undo one specific type of protein damage associated with aging, but the result has only been shown in laboratory-treated samples.** ## Recommended headline **Can an Enzyme Repair Aging Proteins?** ### Standfirst Researchers engineered CMLase to remove a previously hard-to-reverse chemical mark from proteins in laboratory-treated human tissue samples. ### Alternative social headline **Scientists Taught an Enzyme to Undo One Form of Protein Aging** Do not use “Scientists reversed aging,” “Age reversal,” “Rejuvenation enzyme,” or any headline that implies a treatment has been tested in a living person. ## Format and outputs - Master composition: 1080 × 1920 px, vertical 9:16. - High-resolution export: 2160 × 3840 px PNG. - Editable source: Figma preferred; Adobe Illustrator or layered SVG acceptable. - Web export: 108